Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873809 | 0.79 | PDE3B (0.46) | PDE3BPDE3AALDH1A1RXFP1LMNA | |
| SCHEMBL12838844 | 0.75 | KMT2A (0.40) | RXFP1SMN1; SMN2LMNAHTT | |
| SCHEMBL10794183 | 0.74 | KMT2A (0.39) | ALDH1A1RXFP1SMN1; SMN2LMNAHTT | |
| SCHEMBL23233751 | 0.73 | BRD4 (0.48) | PDE3BPDE3AALDH1A1BRD4KDM4E | |
| SCHEMBL23233750 | 0.72 | BRD4 (0.50) | PDE3BPDE3ABRD4 | |
| SCHEMBL11494803 | 0.71 | PDE3B (0.43) | PDE3BPDE3AALDH1A1BRD4KDM4E | |
| SCHEMBL11831603 | 0.70 | PDE3B (0.40) | PDE3BPDE3AALDH1A1RXFP1LMNA | |
| SCHEMBL22588426 | 0.70 | CTRC (0.41) | PDE3BPDE3ABRD4KDM4E | |
| SCHEMBL12775686 | 0.69 | KMT2A (0.39) | ALDH1A1RXFP1SMN1; SMN2LMNAHTT | |
| SCHEMBL11550337 | 0.69 | BRD4 (0.59) | ALDH1A1SMN1; SMN2LMNABRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171429-A | Pyrimidine to pyrimidine transformation process | RESEARCH CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |