Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.59 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.59 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.59 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408034 | 0.88 | TSHR (0.72) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL12012375 | 0.86 | TSHR (1.00) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL12010879 | 0.84 | TSHR (0.81) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL12903642 | 0.78 | TSHR (0.70) | TSHRKMT2AMEN1POLBMAPT | |
| Trimethylammonium SCHEMBL10943396 | 0.77 | MAPT (0.77) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL16358830 | 0.76 | TSHR (0.68) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL11550738 | 0.76 | HTT (0.73) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL13306091 | 0.76 | CA1 (0.75) | TSHRKMT2AMEN1POLBMAPT | |
| Sulfuric Acid SCHEMBL11294286 | 0.76 | MAPT (0.74) | TSHRKMT2AMEN1POLBMAPT | |
| Trimethylammonium SCHEMBL11770098 | 0.76 | MAPT (0.74) | TSHRKMT2AMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |