Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.60 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.60 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.60 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545658 | 0.88 | TSHR (0.75) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL12010879 | 0.85 | TSHR (0.81) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL12012375 | 0.84 | TSHR (1.00) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL12903642 | 0.79 | TSHR (0.70) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL16358830 | 0.77 | TSHR (0.68) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL12197889 | 0.76 | NPC1 (0.77) | TSHRKMT2AMEN1POLBMAPT | |
| SCHEMBL8492310 | 0.76 | ABCC9 (1.00) | TSHRKMT2AMEN1MAPTHTT | |
| SCHEMBL13454566 | 0.76 | MAPT (1.00) | TSHRKMT2AMEN1MAPTHTT | |
| SCHEMBL8643793 | 0.75 | MEN1 (0.65) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL15836648 | 0.75 | ALDH1A1 (1.00) | TSHRKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | claimed |