Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470504 | 0.89 | MAPT (0.40) | MAPTLMNAALDH1A1PRKCAPRKCE | |
| SCHEMBL99241 | 0.83 | TSHR (0.41) | MAPTLMNAALDH1A1PRKCATSHR | |
| SCHEMBL5603928 | 0.82 | TDP1 (0.33) | FAAHCNR1CNR2TDP1 | |
| SCHEMBL7702298 | 0.82 | TDP1 (0.33) | FAAHCNR1CNR2TDP1 | |
| SCHEMBL11548578 | 0.79 | DGKA (0.47) | LMNAALDH1A1FAAHCYP3A4TSHR | |
| SCHEMBL10796247 | 0.78 | MAPT (0.35) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL1684087 | 0.78 | CYP3A4 (0.60) | LMNAALDH1A1CYP3A4TSHRATM | |
| SCHEMBL28449038 | 0.78 | CYP3A4 (0.60) | LMNAALDH1A1CYP3A4TSHRATM | |
| SCHEMBL98954 | 0.77 | TSHR (0.35) | PRKCATSHR | |
| SCHEMBL99109 | 0.77 | TSHR (0.35) | PRKCATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179432-A | 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1979-12-18 | — | — | US | disclosed |