Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545701 | 0.89 | MAPT (0.37) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL11548578 | 0.82 | DGKA (0.47) | TSHRLMNAALDH1A1CYP3A4ATM | |
| SCHEMBL10796247 | 0.82 | MAPT (0.35) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL16389873 | 0.82 | TSHR (0.46) | MAPTTSHRALDH1A1TDP1KDM4E | |
| SCHEMBL2136463 | 0.82 | — | — | |
| SCHEMBL1684087 | 0.81 | CYP3A4 (0.60) | TSHRLMNAALDH1A1CYP3A4ATM | |
| SCHEMBL28449038 | 0.81 | CYP3A4 (0.60) | TSHRLMNAALDH1A1CYP3A4ATM | |
| SCHEMBL9470931 | 0.81 | MAPT (0.41) | MAPTTSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL22091877 | 0.80 | NAAA (0.44) | TSHRDGKA | |
| SCHEMBL338603 | 0.80 | NAAA (0.44) | TSHRDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244995-A | Vinyl halide aqueous polymerization dispersant system | THE BF GOODRICH COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5155189-A | Derived from repeating units of acrylic and/or methacrylic ester polymers | THE B. F. GOODRICH COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0501300-A1 | High melt flow crosslinked PVC resin, compound and articles derived therefrom | The Geon Company (US) | 1992-09-02 | — | — | EP | disclosed |
| EP-0483051-A1 | Improved vinyl halide aqueous polymerization dispersant system | The Geon Company (US) | 1992-04-29 | — | — | EP | disclosed |
| EP-0473915-A1 | Improved barrier PVC resins, compounds and articles derived therefrom | THE B.F. GOODRICH COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |