Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23812525 | 0.92 | GAA (0.84) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL1276402 | 0.92 | GAA (0.84) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9243020 | 0.87 | ALDH1A1 (0.81) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11684405 | 0.85 | ALDH1A1 (0.77) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11546140 | 0.84 | GAA (0.72) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8956322 | 0.80 | ALDH1A1 (0.94) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11828149 | 0.79 | MAPT (0.73) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL132620 | 0.78 | ALDH1A1 (1.00) | GAAMAPTCYP1A2CYP2C19KMT2A | |
| SCHEMBL2590098 | 0.77 | CYP1A2 (0.64) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11550071 | 0.77 | MAPT (0.67) | GAAMAPTSMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |