Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276402 | 1.00 | GAA (0.84) | GAAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11684405 | 0.93 | ALDH1A1 (0.77) | GAAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11545867 | 0.92 | GAA (1.00) | GAAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11546140 | 0.87 | GAA (0.72) | GAAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL132620 | 0.85 | ALDH1A1 (1.00) | GAAMAPTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL14360821 | 0.84 | ALDH1A1 (0.70) | GAAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11828149 | 0.82 | MAPT (0.73) | GAAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9470190 | 0.82 | ALDH1A1 (0.94) | GAAMAPTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8956322 | 0.82 | ALDH1A1 (0.94) | GAAMAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9526913 | 0.82 | GAA (0.75) | GAAMAPTCYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283271-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283271-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | IGF2R, CFH, M6PR | GAA 1009/4885MAPT 1734/4885CYP1A2 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.