Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.50 |
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021281 | 0.83 | NAPRT (0.53) | MAPTTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL11545880 | 0.78 | KDM4E (0.53) | MAPTALDH1A1MAPK1USP2HPGD | |
| SCHEMBL28882091 | 0.77 | ALDH1A1 (0.69) | MAPTPOLBALDH1A1PKMMAPK1 | |
| SCHEMBL30058951 | 0.76 | ALDH1A1 (0.68) | MAPTALDH1A1PKMMAPK1NPSR1 | |
| SCHEMBL27331342 | 0.75 | KDM4E (0.64) | MAPTPOLBALDH1A1MAPK1NPSR1 | |
| SCHEMBL28859929 | 0.72 | HPGD (0.66) | MAPTPOLBALDH1A1MAPK1NPSR1 | |
| SCHEMBL16055320 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1PKMNPSR1MEN1 | |
| SCHEMBL27083786 | 0.70 | HPGD (0.68) | MAPTPOLBALDH1A1MAPK1NPSR1 | |
| SCHEMBL8306889 | 0.70 | RXFP1 (0.58) | MAPTPOLBRECQLCTDSP1TDP1 | |
| SCHEMBL14003400 | 0.70 | CYP2A6 (0.54) | MAPTTDP1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163855-A | Azetidine compounds and process for production | PHILIP MORRIS INCORPORATED (US) | 1979-08-07 | — | — | US | disclosed |
| US-4163856-A | Azetidine compounds and process for production | PHILIP MORRIS INCORPORATED (US) | 1979-08-07 | — | — | US | disclosed |