Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304200 | 0.85 | MAPT (0.59) | RXFP1LMNATHRBCYP2C9ALDH1A1 | |
| SCHEMBL8304700 | 0.82 | MAPK1 (0.49) | RXFP1LMNAMAPK1ALDH1A1USP2 | |
| SCHEMBL8303960 | 0.81 | RXFP1 (0.65) | RXFP1LMNATHRBMAPK1ALDH1A1 | |
| SCHEMBL8305679 | 0.81 | RXFP1 (0.71) | RXFP1LMNATHRBALDH1A1KMT2A | |
| SCHEMBL8311182 | 0.78 | RXFP1 (0.61) | RXFP1LMNATHRBALDH1A1HPGD | |
| SCHEMBL8305681 | 0.77 | RXFP1 (0.66) | RXFP1LMNATHRBCYP2C9ALDH1A1 | |
| SCHEMBL8305683 | 0.77 | RXFP1 (0.60) | RXFP1LMNATHRBALDH1A1HPGD | |
| SCHEMBL7821284 | 0.74 | KMT2A (0.81) | RXFP1LMNACYP2C9DHODHALDH1A1 | |
| SCHEMBL19475274 | 0.74 | ALDH1A1 (0.71) | RXFP1LMNACYP2C9MAPK1DHODH | |
| SCHEMBL18320684 | 0.74 | KDM4E (0.78) | RXFP1LMNACYP2C9MAPK1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |