SCHEMBL115459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL165406	0.91	CXCR3 (0.43)	CXCR3
	SCHEMBL3726521	0.90	CXCR3 (0.51)	CXCR3
	SCHEMBL3736137	0.89	CXCR3 (0.54)	CXCR3
	SCHEMBL3726519	0.89	CXCR3 (0.55)	CXCR3
	SCHEMBL3724591	0.89	CXCR3 (0.53)	CXCR3THRB
	SCHEMBL175994	0.89	CXCR3 (0.53)	CXCR3
	SCHEMBL165563	0.88	GRM5 (0.41)	CXCR3THRBPOLB
	SCHEMBL3728877	0.86	CXCR3 (0.52)	CXCR3
	SCHEMBL3739124	0.83	CXCR3 (0.53)	CXCR3POLB
	SCHEMBL116694	0.81	CXCR3 (0.55)	CXCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.