Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115459 | 0.91 | CXCR3 (0.48) | CXCR3 | |
| SCHEMBL165563 | 0.91 | GRM5 (0.41) | CXCR3KCNH2 | |
| SCHEMBL3739124 | 0.85 | CXCR3 (0.53) | CXCR3KCNH2 | |
| SCHEMBL3735661 | 0.85 | CXCR3 (0.46) | CXCR3KCNH2 | |
| SCHEMBL3726521 | 0.82 | CXCR3 (0.51) | CXCR3KCNH2 | |
| SCHEMBL163154 | 0.82 | GRM5 (0.43) | CXCR3KCNH2 | |
| SCHEMBL3736137 | 0.81 | CXCR3 (0.54) | CXCR3KCNH2 | |
| SCHEMBL165659 | 0.81 | CXCR3 (0.48) | CXCR3KCNH2 | |
| SCHEMBL3735551 | 0.81 | GRM5 (0.46) | CXCR3 | |
| SCHEMBL3726519 | 0.81 | CXCR3 (0.55) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424840-A1 | CXCR3 RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126811-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-04 | — | — | WO | disclosed |