SCHEMBL11545901

SCHEMBL11545901

Cc1ccc(C2OC(=O)c3ccccc32)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.73
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
LMNA P02545 1/20 0.49
MAOB P27338 1/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
CYP19A1 P11511 1/20 0.43
TNKS2 Q9H2K2 1/20 0.42
PAX8 Q06710 1/20 0.42
NR3C1 P04150 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31322079 0.93 ALDH1A1 (0.64) ALDH1A1CA1CA2CA9MEN1
SCHEMBL11073378 0.89 ALDH1A1 (0.59) ALDH1A1CA1CA2CA9MEN1
SCHEMBL247073 0.85 ALDH1A1 (1.00) ALDH1A1CA1CA2CA9MEN1
SCHEMBL10895239 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9MEN1
SCHEMBL7106401 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9MEN1
SCHEMBL863475 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9MEN1
SCHEMBL10786395 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9MEN1
SCHEMBL337709 0.81 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9MEN1
SCHEMBL11543103 0.81 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9LMNA
SCHEMBL11547373 0.81 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105199815-A High-ash type oilfield associated gas engine lubricating oil composition TIANJIN ZHONGDA PETROCHEMICAL CO LTD 2015-12-30 CN disclosed
CN-105112127-A Medium-ash type lubricating oil composition for oil-gas mixed engine TIANJIN ZHONGDA PETROCHEMICAL CO LTD 2015-12-02 CN disclosed
CN-105062648-A Low-ash type gas engine lubricating oil composition TIANJIN ZHONGDA PETROCHEMICAL CO LTD 2015-11-18 CN disclosed
US-4175191-A 4-Phenyl isoquinolines SANDOZ, INC. (US) 1979-11-20 US disclosed
US-3989704-A 3-Substituted-4-aryl isoquinolines SANDOZ, INC. (US) 1976-11-02 US disclosed