SCHEMBL7106401

SCHEMBL7106401

O=C1OC(c2ccc(F)cc2)c2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
KDM4E B2RXH2 2/20 0.46
MAOB P27338 2/20 0.46
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP19A1 P11511 1/20 0.43
NR3C1 P04150 1/20 0.40
USP1 O94782 1/20 0.39
WDR48 Q8TAF3 1/20 0.39
FADS1 O60427 1/20 0.39
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247073 0.85 ALDH1A1 (1.00) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL11545901 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL10786395 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL10895239 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL863475 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL17737240 0.79 ALDH1A1 (0.73) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL9303033 0.78 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL11543103 0.78 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9MAOB
SCHEMBL337709 0.78 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9KDM4E
SCHEMBL29032508 0.78 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1032566-B9 METHOD FOR THE PREPARATION OF CITALOPRAM LUNDBECK & CO AS H (DK) 2003-10-22 EP disclosed
EP-1032566-B1 METHOD FOR THE PREPARATION OF CITALOPRAM LUNDBECK & CO AS H (DK) 2003-02-12 EP disclosed
EP-1032566-A2 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2000-09-06 EP disclosed
WO-1998019511-A3 METHOD FOR THE PREPARATION OF CITALOPRAM LUNDBECK & CO AS H (DK) 1998-08-06 WO disclosed
WO-1998019511-A2 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 1998-05-14 WO disclosed