Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752154 | 0.79 | TSHR (0.47) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL18912736 | 0.77 | TSHR (0.45) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL11742981 | 0.77 | TSHR (0.45) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL27766988 | 0.75 | TSHR (0.42) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL19499070 | 0.73 | TSHR (0.41) | TSHR | |
| SCHEMBL234712 | 0.70 | ALDH1A1 (0.39) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL1994296 | 0.70 | TSHR (0.50) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL28887767 | 0.70 | TSHR (0.38) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL1282258 | 0.69 | TSHR (0.48) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL28077512 | 0.69 | TSHR (0.48) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30142-E | FOR LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 1979-11-06 | — | — | US | disclosed |
| US-4070385-A | HYDRAULIC FLUID ADDITIVES | THE LUBRIZOL CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-4026812-A | HYDRAULIC FLUIDS, OIL IN WATER EMULSIONS | THE LUBRIZOL CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |