SCHEMBL8752154

SCHEMBL8752154

C=CC(=O)NC(NC(=O)C=C)C(C)(C)S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
CYP2C19 P33261 2/20 0.33
TGM2 P21980 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11742981 0.98 TSHR (0.45) TSHRCYP2C19TGM2ZDHHC20ZDHHC2
SCHEMBL19499070 0.93 TSHR (0.41) TSHR
SCHEMBL18912736 0.83 TSHR (0.45) TSHRCYP2C19TGM2ZDHHC20ZDHHC2
SCHEMBL1994296 0.83 TSHR (0.50) TSHRCYP2C19TGM2ZDHHC20ZDHHC2
SCHEMBL26026748 0.81 TSHR (0.44) TSHRCYP2C19TGM2ZDHHC20ZDHHC2
SCHEMBL11545939 0.79 TSHR (0.41) TSHRCYP2C19ZDHHC20ZDHHC2ALDH1A1
SCHEMBL21281463 0.76 TSHR (0.39) TSHRTGM2ZDHHC20ZDHHC2ALDH1A1
Acrylic Acid SCHEMBL8742887 0.76 TSHR (0.39) TSHRTGM2
SCHEMBL11742079 0.75 POLB (0.30)
SCHEMBL1282258 0.74 TSHR (0.48) TSHRCYP2C19TGM2ZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4600057-A Method of reducing the permeability of a subterranean formation HALLIBURTON COMPANY (US) 1986-07-15 US claimed
EP-0180406-A2 Method of treating a subterranean formation HALLIBURTON COMPANY (US) 1986-05-07 EP claimed
US-RE30142-E FOR LUBRICANTS THE LUBRIZOL CORPORATION (US) 1979-11-06 US claimed
US-20230347333-A1 Membranes FUJIFILM CORPORATION (JP) 2023-11-02 US disclosed
US-20230347333-A1 Membranes FUJIFILM CORPORATION (JP) 2023-11-02 US disclosed
US-20230311071-A1 Composite Membrane FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2023-10-05 US disclosed
US-20230311071-A1 Composite Membrane FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2023-10-05 US disclosed
US-20230028028-A1 Affinity Membranes, Compounds, Compositions and Processes for Their Preparation and Use FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2023-01-26 US disclosed
WO-2022122931-A1 PURIFYING POLAR LIQUIDS FUJIFILM MANUFACTURING EUROPE BV (NL) 2022-06-16 WO disclosed
EP-3245234-B1 CURABLE COMPOSITIONS AND MEMBRANES FUJIFILM MFG EUROPE BV (NL) 2019-08-21 EP disclosed
US-10336873-B2 Functional polymer membrane, manufacturing method therefor, ion exchange membrane and proton conductive membrane equipped with functional polymer membrane, and ion exchange device FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-4960761-A High surface area polymers of pyrrole or copolymers of pyrrole THE LUBRIZOL CORPORATION (US) 1990-10-02 US disclosed
US-4921890-A Process for improving polymer substrate properties, and flame retardancy modified polymers produced thereby INTERA COMPANY, LTD. (US) 1990-05-01 US disclosed
US-4839322-A ELECTROCONDUCTIVE SURFACE; CATALYST THE LUBRIZOL CORPORATION (US) 1989-06-13 US disclosed
EP-0294531-A2 Treatment of polymer substrates Intera Company, Ltd (US) 1988-12-14 EP disclosed
US-4791374-A IN LUBRICATING OIL OF INTERNAL COMBUSTION AND DIESEL ENGINES USING AN ELECTROCONDUCTIVE POLYMER THE LUBRIZOL CORPORATION (US) 1988-12-13 US disclosed
US-4726968-A EMULSION POLYMERIZATION OF WATER-SOLUBLE CROSSLINKING VINYL MONOMER INTERA COMPANY, LTD., A TENNESSEE LIMITED PARTNERSHIP (US) 1988-02-23 US disclosed
US-4600057-A Method of reducing the permeability of a subterranean formation HALLIBURTON COMPANY (US) 1986-07-15 US disclosed
EP-0180406-A2 Method of treating a subterranean formation HALLIBURTON COMPANY (US) 1986-05-07 EP disclosed
US-4034001-A MONOMERS THE LUBRIZOL CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230028028-A1 Affinity Membranes, Compounds, Compositions and Processes for Their Preparation and Use MLEC, PGRMC1, PICALM TSHR 4773/4885CYP2C19 2692/4885TGM2 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.