Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ATF4 | P18848 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544180 | 0.86 | HSD17B10 (0.70) | ADAMTS5HSD17B10HPGDKMT2ACYP1A2 | |
| SCHEMBL11547907 | 0.86 | HSD17B10 (0.46) | ADAMTS5HSD17B10HPGDATF4KMT2A | |
| SCHEMBL11547612 | 0.83 | HSD17B10 (0.49) | ADAMTS5HSD17B10HPGDATF4KMT2A | |
| SCHEMBL11547340 | 0.83 | HSD17B10 (0.52) | ADAMTS5HSD17B10HPGDATF4KMT2A | |
| SCHEMBL11545033 | 0.83 | ADAMTS5 (0.53) | ADAMTS5HSD17B10HPGDKMT2ACYP1A2 | |
| SCHEMBL11546202 | 0.83 | HPGD (0.67) | ADAMTS5HSD17B10HPGDKMT2ACYP1A2 | |
| SCHEMBL11545981 | 0.81 | HSD17B10 (0.49) | ADAMTS5HSD17B10HPGDKMT2ACYP1A2 | |
| SCHEMBL11546891 | 0.79 | HSD17B10 (0.57) | HSD17B10HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL11527702 | 0.79 | KMT2A (0.49) | HPGDATF4KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11640701 | 0.79 | HTT (0.53) | HPGDKMT2ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164576-A | LIPOGENESIS INHIBITORS IN MAMMALS | SHELL OIL COMPANY (US) | 1979-08-14 | — | — | US | disclosed |