Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | ATF4 | P18848 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528144 | 0.85 | CYP4F2 (0.47) | KMT2AMEN1HPGDCYP1A2CYP3A4 | |
| SCHEMBL11530821 | 0.84 | LMNA (0.47) | KMT2AMEN1HPGDPOLBCYP4F2 | |
| SCHEMBL11525477 | 0.82 | POLB (0.48) | KMT2AMEN1HPGDPOLBCYP4F2 | |
| SCHEMBL11527340 | 0.81 | CYP4F2 (0.39) | KMT2AMEN1HPGDCYP4F2CYP4A11 | |
| SCHEMBL11527877 | 0.81 | PPARG (0.52) | NFKB1NFKB2RELARAB9AHTT | |
| SCHEMBL11580216 | 0.81 | HTT (0.53) | KMT2AMEN1HPGDCYP1A2CYP3A4 | |
| SCHEMBL11640701 | 0.81 | HTT (0.53) | KMT2AMEN1HPGDCYP1A2CYP3A4 | |
| SCHEMBL24496756 | 0.80 | MEN1 (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23552434 | 0.79 | MEN1 (0.46) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11546162 | 0.79 | ADAMTS5 (0.53) | KMT2AMEN1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178380-A | LIPOGENSIS INHIBITORS | SHELL OIL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4103021-A | BENZODIOXIN AND BENZOPYRAN CARBOXAMIDES | SHELL OIL COMPANY (US) | 1978-07-25 | — | — | US | disclosed |