Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307181 | 0.87 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9307179 | 0.87 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9307177 | 0.87 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL13969391 | 0.82 | SIGMAR1 (0.65) | SIGMAR1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL9448135 | 0.78 | SRD5A1 (0.58) | SIGMAR1HTR1A | |
| SCHEMBL9448222 | 0.78 | SRD5A1 (0.58) | SIGMAR1HTR1A | |
| SCHEMBL9448145 | 0.78 | SRD5A1 (0.58) | SIGMAR1HTR1A | |
| SCHEMBL9448141 | 0.78 | SRD5A1 (0.58) | SIGMAR1HTR1A | |
| SCHEMBL9448218 | 0.78 | SRD5A1 (0.58) | SIGMAR1HTR1A | |
| SCHEMBL861127 | 0.77 | SIGMAR1 (0.63) | SIGMAR1MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166183-A | TRICYCLIC CYCLITOLAMINES | E. R. SQUIBB & SONS, INC. (US) | 1979-08-28 | — | — | US | disclosed |