Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448222 | 1.00 | SRD5A1 (0.58) | SRD5A1SIGMAR1HTR1A | |
| SCHEMBL9448141 | 1.00 | SRD5A1 (0.58) | SRD5A1SIGMAR1HTR1A | |
| SCHEMBL9448135 | 1.00 | SRD5A1 (0.58) | SRD5A1SIGMAR1HTR1A | |
| SCHEMBL9448218 | 1.00 | SRD5A1 (0.58) | SRD5A1SIGMAR1HTR1A | |
| SCHEMBL11546208 | 0.78 | SIGMAR1 (0.77) | SIGMAR1HTR1A | |
| SCHEMBL18779969 | 0.78 | SRD5A1 (0.57) | SRD5A1SIGMAR1HTR1A | |
| SCHEMBL18779970 | 0.78 | SRD5A1 (0.57) | SRD5A1SIGMAR1HTR1A | |
| SCHEMBL9448162 | 0.78 | ADRA1B (0.53) | — | |
| SCHEMBL9448354 | 0.76 | SIGMAR1 (0.56) | SRD5A1SIGMAR1 | |
| SCHEMBL9448360 | 0.76 | SIGMAR1 (0.56) | SRD5A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |