Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 6/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542763 | 0.79 | KDM4E (0.47) | RAB9AALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL4451342 | 0.79 | MCL1 (0.55) | KCNH2MCL1RAB9AAHRALDH1A1 | |
| SCHEMBL4452101 | 0.79 | MCL1 (0.51) | KCNH2MCL1RAB9AAHRALDH1A1 | |
| SCHEMBL11551444 | 0.78 | PIK3CA (0.42) | KCNH2DYRK1A | |
| SCHEMBL11542250 | 0.77 | KCNH2 (0.53) | KCNH2RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL11545978 | 0.74 | MCL1 (0.61) | KCNH2MCL1RAB9AALDH1A1HPGD | |
| SCHEMBL3079524 | 0.74 | HSD17B3 (0.57) | KCNH2MCL1ALDH1A1MAPTHPGD | |
| SCHEMBL14409919 | 0.72 | MCL1 (0.59) | KCNH2MCL1AHRALDH1A1LMNA | |
| SCHEMBL11442225 | 0.71 | AHR (0.51) | KCNH2AHRCYP2A6ALDH1A1NQO1 | |
| SCHEMBL25824628 | 0.69 | MCL1 (0.56) | KCNH2MCL1AHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172145-A | ANALGESICS, ANTIPYRETICS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | disclosed |
| US-4126625-A | ANTIPHLOGISTIC, ANALGESIC | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1978-11-21 | — | — | US | disclosed |