Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542270 | 0.84 | MAPT (0.54) | KCNH2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11542872 | 0.83 | RAB9A (0.46) | MCL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4451342 | 0.81 | MCL1 (0.55) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL11543638 | 0.79 | PON1 (0.45) | MCL1KDM4EALDH1A1 | |
| SCHEMBL11544887 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL11544580 | 0.79 | L3MBTL1 (0.45) | KDM4ECA12CA9 | |
| SCHEMBL8401455 | 0.79 | LMNA (0.47) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL8399463 | 0.78 | CA1 (0.52) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4452101 | 0.78 | MCL1 (0.51) | MCL1KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL7030133 | 0.78 | KCNH2 (0.48) | KCNH2KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172145-A | ANALGESICS, ANTIPYRETICS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | claimed |
| US-4172145-A | ANALGESICS, ANTIPYRETICS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | disclosed |
| US-4126625-A | ANTIPHLOGISTIC, ANALGESIC | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1978-11-21 | — | — | US | disclosed |