Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380818 | 0.85 | PRCP (0.33) | PRCPDPP7TLR2CYP2D6MEN1 | |
| SCHEMBL11546726 | 0.80 | GHSR (0.38) | CYP2D6DPP4DPP8 | |
| SCHEMBL11545180 | 0.78 | PRCP (0.34) | PRCPDPP7SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11546816 | 0.77 | PRCP (0.33) | PRCPDPP7SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11618241 | 0.76 | PRCP (0.38) | PRCPDPP7SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7380845 | 0.76 | PRCP (0.35) | PRCPDPP7TLR2CYP2D6DPP4 | |
| SCHEMBL9362980 | 0.75 | PRCP (0.44) | PRCPDPP7TLR2DPP4DPP8 | |
| SCHEMBL30265157 | 0.75 | PRCP (0.44) | PRCPDPP7TLR2DPP4DPP8 | |
| SCHEMBL11378883 | 0.75 | PRCP (0.34) | PRCPDPP7TLR2 | |
| SCHEMBL11558591 | 0.75 | SLC6A2 (0.39) | PRCPDPP7SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |