Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.49 |
| ▸ | NMT1 | P30419 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363690 | 0.90 | AOC3 (0.54) | AOC3ADRB1PLD1NMT1MAOB | |
| SCHEMBL11919149 | 0.88 | ADRB1 (0.55) | AOC3ADRB1PLD1NMT1MAOB | |
| Hydrochloric Acid SCHEMBL31061226 | 0.86 | ADRB1 (0.54) | AOC3ADRB1PLD1NMT1MAOB | |
| SCHEMBL15621623 | 0.86 | HRH4 (0.49) | AOC3HRH4OPRM1OPRL1 | |
| SCHEMBL24507651 | 0.83 | HRH4 (0.54) | AOC3HTR6HRH3HRH4OPRM1 | |
| SCHEMBL13069962 | 0.82 | PIK3CA (0.53) | OPRM1OPRL1 | |
| SCHEMBL22792040 | 0.82 | HRH3 (0.42) | AOC3HRH3HRH4 | |
| SCHEMBL2328273 | 0.81 | AOC3 (0.56) | AOC3ADRB1PLD1NMT1MAOB | |
| SCHEMBL13361855 | 0.81 | ADRB1 (0.59) | AOC3ADRB1PLD1NMT1MAOB | |
| SCHEMBL23630504 | 0.79 | AOC3 (0.60) | AOC3ADRB1PLD1NMT1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |