Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.48 |
| ▸ | NMT1 | P30419 | 6/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546296 | 0.90 | AOC3 (0.57) | AOC3ADRB1HRH4NMT1PLD1 | |
| SCHEMBL11919149 | 0.84 | ADRB1 (0.55) | AOC3ADRB1HRH4NMT1PLD1 | |
| SCHEMBL21376960 | 0.83 | PIK3CA (0.50) | OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL31061226 | 0.82 | ADRB1 (0.54) | AOC3ADRB1HRH4NMT1PLD1 | |
| SCHEMBL13361855 | 0.78 | ADRB1 (0.59) | AOC3ADRB1HRH4NMT1PLD1 | |
| SCHEMBL2328273 | 0.78 | AOC3 (0.56) | AOC3ADRB1HRH4NMT1PLD1 | |
| SCHEMBL3640716 | 0.78 | HRH3 (0.52) | ADRB1HRH4PLD1HTR6HRH3 | |
| SCHEMBL4563936 | 0.78 | HTR2C (0.37) | AOC3HRH4HTR2AHTR2C | |
| SCHEMBL15621623 | 0.76 | HRH4 (0.49) | AOC3HRH4OPRM1OPRL1 | |
| SCHEMBL23630504 | 0.76 | AOC3 (0.60) | AOC3ADRB1HRH4NMT1PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385237-B1 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5021421-A | Psychotropic agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0385237-A2 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |