SCHEMBL11546306

SCHEMBL11546306

CCC(C)C(C#N)c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
SLC6A4 P31645 1/20 0.38
ADRA2A P08913 3/20 0.37
ADRA2B P18089 3/20 0.37
ADRA2C P18825 3/20 0.37
ADRA1A P35348 2/20 0.37
ADRA1D P25100 1/20 0.37
ADRA1B P35368 1/20 0.37
AOC3 Q16853 1/20 0.37
KMT2A Q03164 1/20 0.37
CASR P41180 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11545332 0.86 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL11214387 0.80 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL29061989 0.80 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL20363442 0.78 ALDH1A1 (0.48) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL3673978 0.77 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A
SCHEMBL10399086 0.75 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL28411073 0.75 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL15211048 0.73 TSHR (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL2127427 0.73 TSHR (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL18803297 0.72 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164415-A Branched alkyl-2-naphthaleneacetic acids as herbicides and insecticide intermediates AMERICAN CYANAMID CO. (US) 1979-08-14 US disclosed
US-4088782-A Substituted-benzyl α-C1 -C4 alkyl-2-naphthaleneacetates as insecticidal agents AMERICAN CYANAMID COMPANY (US) 1978-05-09 US disclosed
US-4046799-A INSECTICIDES AMERICAN CYANAMID COMPANY (US) 1977-09-06 US disclosed