SCHEMBL11547149

SCHEMBL11547149

Cc1c(Br)c(Br)cc(C(Br)(Br)Br)c1Br

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.33
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11553167 0.80 APEX1 (0.33) APEX1CA2CA4
SCHEMBL518115 0.80
SCHEMBL1547096 0.78 APEX1 (0.44) APEX1CA2CA4
SCHEMBL9376593 0.70 APEX1 (0.38) APEX1CA2CA4
SCHEMBL7754486 0.67 CA1 (0.40) APEX1CA2CA4
SCHEMBL21218762 0.65 APEX1 (0.38) APEX1CA2CA4
SCHEMBL6690082 0.65 APEX1 (0.38) APEX1CA2CA4
SCHEMBL2954135 0.64 SOS1 (0.32)
SCHEMBL2242584 0.62 ALDH1A1 (0.33) CA2
SCHEMBL9464685 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4171456-A α,α'-Bis(2-hydroxyethoxy)-2,3,5,6-tetrabromo-p-xylene ETHYL CORPORATION (US) 1979-10-16 US disclosed