Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886516 | 0.95 | DNM1 (0.48) | TLR2HTTDNM1MEN1KMT2A | |
| SCHEMBL8346718 | 0.95 | DNM1 (0.48) | TLR2HTTDNM1MEN1KMT2A | |
| SCHEMBL11879346 | 0.86 | DNM1 (0.46) | TLR2HTTDNM1MEN1KMT2A | |
| SCHEMBL10879025 | 0.86 | DNM1 (0.47) | HTTDNM1MAPTUSP2 | |
| SCHEMBL21693799 | 0.86 | DNM1 (0.47) | HTTDNM1MAPTUSP2 | |
| SCHEMBL5511038 | 0.86 | DNM1 (0.47) | HTTDNM1MAPTUSP2 | |
| SCHEMBL11119607 | 0.86 | DNM1 (0.47) | HTTDNM1MAPTUSP2 | |
| SCHEMBL1465743 | 0.86 | DNM1 (0.47) | HTTDNM1MAPTUSP2 | |
| SCHEMBL9859145 | 0.86 | DNM1 (0.47) | HTTDNM1MAPTUSP2 | |
| SCHEMBL725926 | 0.86 | DNM1 (0.47) | HTTDNM1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134842-A | Molded plastic bearing assembly | KAMATICS CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4053665-A | MOLDED PLASTIC BEARING ASSEMBLY | KAMATICS CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4048370-A | Shaped bearing member | KAMATICS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-3996143-A | Cured acrylate bearing member | KAMATICS CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |