Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 4/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346718 | 1.00 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11547346 | 0.95 | TLR2 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11879346 | 0.91 | DNM1 (0.46) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1465743 | 0.90 | DNM1 (0.47) | DNM1SPHK1HTT | |
| SCHEMBL21693799 | 0.90 | DNM1 (0.47) | DNM1SPHK1HTT | |
| SCHEMBL11119607 | 0.90 | DNM1 (0.47) | DNM1SPHK1HTT | |
| SCHEMBL9859145 | 0.90 | DNM1 (0.47) | DNM1SPHK1HTT | |
| SCHEMBL5511038 | 0.90 | DNM1 (0.47) | DNM1SPHK1HTT | |
| SCHEMBL725926 | 0.90 | DNM1 (0.47) | DNM1SPHK1HTT | |
| SCHEMBL10879025 | 0.90 | DNM1 (0.47) | DNM1SPHK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072605-A1 | IONIZABLE AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |