SCHEMBL11547360

SCHEMBL11547360

CCC=C(C(=O)O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338910 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11553004 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11548213 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11553649 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL4145565 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL2689506 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11552746 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11548737 0.98 THRB (0.43) THRBGRIK1GRIK2
SCHEMBL338873 0.89 THRB (0.35) THRB
SCHEMBL5029210 0.83 THRB (0.33) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4178329-A Plastics material having an improved blood tolerance HOECHST AKTIENGESELLSCHAFT (DE) 1979-12-11 US disclosed