SCHEMBL338910

SCHEMBL338910

CCC=C(C(=O)O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11553004 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11548213 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11553649 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL4145565 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL2689506 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11552746 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11547360 1.00 THRB (0.47) THRBMAPTGAAALDH1A1RECQL
SCHEMBL11548737 0.98 THRB (0.43) THRBGRIK1GRIK2
SCHEMBL338873 0.89 THRB (0.35) THRB
SCHEMBL5029210 0.83 THRB (0.33) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11970662-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2024-04-30 US disclosed
EP-3771736-B1 ELECTROCHROMIC ELEMENT RICOH CO LTD (JP) 2023-11-15 EP disclosed
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
WO-2022113702-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2022-06-02 WO disclosed
EP-3712695-B1 ELECTROCHROMIC DEVICE, WEARABLE DEVICE, AND METHOD FOR DRIVING ELECTROCHROMIC DEVICE RICOH CO LTD (JP) 2022-02-23 EP disclosed
EP-3889130-A1 ELECTROCHROMIC ELEMENT Ricoh Company, Ltd. (JP) 2021-10-06 EP disclosed
US-20210301197-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2021-09-30 US disclosed
US-20210032531-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2021-02-04 US disclosed
EP-3771736-A1 ELECTROCHROMIC ELEMENT Ricoh Company, Ltd. (JP) 2021-02-03 EP disclosed
US-20200301226-A1 ELECTROCHROMIC DEVICE, WEARABLE DEVICE, AND METHOD FOR DRIVING ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2020-09-24 US disclosed
US-20050282075-A1 Photoconductor, manufacturing method thereof, image forming process and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2005-12-22 US disclosed
US-20050266325-A1 Outer layer is the crosslinked product of a urethane oligomer having radical polymerizing functional group (e.g., from di(meth)acrylated 1,2,9,10-tetrahydroxy-4,7-dioxadecane), a crosslinking agent, and a reactive charge transport agent, especially acrylated di- or triarylamine; performance & reliability RICOH COMPANY, LTD. (JP) 2005-12-01 US disclosed
US-20050266328-A1 Electrophotographic photoreceptor, and image forming method, apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY LIMITED (JP) 2005-12-01 US disclosed
EP-1600822-A2 Electrophotographic photoreceptor and image forming method, apparatus and process cartridge therefor using the photoreceptor Ricoh Company, Ltd. (JP) 2005-11-30 EP disclosed
US-20050238987-A1 Process cartridge, image forming apparatus, and image forming process RICOH COMPANY, LTD. (JP) 2005-10-27 US disclosed
WO-2005064374-A1 FABRICATION OF POLYMER WAVEGUIDE USING A MOLD LUVANTIX CO. LTD. (KR) 2005-07-14 WO disclosed
WO-2003072625-A1 PHOTOCURABLE RESIN COMPOSITION FOR OPTICAL WAVEGUIDE AND OPTICAL WAVEGUIDE MADE OF THE SAME LUVANTIX CO., LTD. (KR) 2003-09-04 WO disclosed
EP-0572269-B1 Fluorine containing aqueous composition for imparting water and oil repellent properties to textiles HOECHST GOSEI KK (JP) 1998-01-21 EP disclosed
EP-0572269-A1 Fluorine containing aqueous composition having water repellent and oil repellent properties HOECHST GOSEI K.K. (JP) 1993-12-01 EP disclosed
US-4178329-A Plastics material having an improved blood tolerance HOECHST AKTIENGESELLSCHAFT (DE) 1979-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032531-A1 ELECTROCHROMIC ELEMENT TMEM109, DSG1, GPX1 THRB 4504/4885MAPT 3461/4885GAA 3132/4885
US-11970662-B2 Electrochromic element TMEM109, DSG1, GPX1 THRB 4504/4885MAPT 3461/4885GAA 3132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.