SCHEMBL1154749

SCHEMBL1154749

OCC(O)c1cccc(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 8/20 0.49
ADRB1 P08588 5/20 0.49
ADRB2 P07550 4/20 0.49
SLC2A1 P11166 2/20 0.48
IDO1 P14902 2/20 0.47
LMNA P02545 1/20 0.46
ACP3 P15309 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL767795 1.00 ADRB3 (0.49) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL2879198 1.00 ADRB3 (0.49) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL14038059 0.86 TSHR (0.47) ADRB3ADRB1ADRB2LMNA
SCHEMBL1560927 0.85 ADRB3 (0.48) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL3917396 0.85 ADRB3 (0.48) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL7107297 0.85 ADRB3 (0.48) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL7105071 0.85 ADRB3 (0.48) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL8098427 0.85 ADRB3 (0.48) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL98267 0.85 ADRB3 (0.48) ADRB3ADRB1ADRB2SLC2A1IDO1
SCHEMBL23489604 0.83 ADRB3 (0.47) ADRB3ADRB1ADRB2SLC2A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114108014-B Method for synthesizing pinacol by selective electroreduction coupling of active hydrogen-mediated carbonyl compound in water 天津大学 2023-08-11 CN claimed
CN-114108014-A Method for synthesizing pinacol by selective electroreduction coupling of carbonyl compound mediated by active hydrogen in water 天津大学 2022-03-01 CN claimed
EP-4709708-A1 NOVEL CARBOXAMIDE DERIVATIVES ANGELINI PHARMA S.P.A. (IT) 2026-03-18 EP disclosed
EP-4588918-A1 SYNTHESIS OF (S)-1-(1-(3-CHLOROPHENYL)-2-(DIMETHYLAMINO)ETHYL)- 4-(5-MORPHOLINO-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)PYRIDIN-2(1H)-ONE AGV Discovery (FR) 2025-07-23 EP disclosed
US-20250065315-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) 2025-02-27 US disclosed
WO-2024233603-A1 NOVEL CARBOXAMIDE DERIVATIVES ICAGEN, LLC (US) 2024-11-14 WO disclosed
US-20240199612-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN SHIRE HUMAN GENETIC THERAPIES (US) 2024-06-20 US disclosed
EP-4308227-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN Takeda Pharmaceutical Company Limited (JP) 2024-01-24 EP disclosed
CN-117396473-A Imidazopyridinyl inhibitors of plasma kallikrein 武田药品工业株式会社 2024-01-12 CN disclosed
CN-112638917-B Heterocyclic compounds as kinase inhibitors, compositions comprising the same, and methods of use thereof 捷思英达控股有限公司 2023-09-08 CN disclosed
CN-114108014-B Method for synthesizing pinacol by selective electroreduction coupling of active hydrogen-mediated carbonyl compound in water 天津大学 2023-08-11 CN disclosed
US-6103759-A COMPRISING PURE ENANTIOMERIC FORMS, AS WELL AS ENANTIOMERIC MIXTURES, OF (2-(2-CHLOROPHENYL)-2-HYDROXYETHYL)OXYCARBOXAMIDE; USEFUL FOR TRATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS SK CORPORATION (US) 2000-08-15 US disclosed
WO-2000009463-A1 STEREOSELECTIVE RING OPENING REACTIONS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-24 WO disclosed
EP-0934264-A1 PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS PFIZER INC. (US) 1999-08-11 EP disclosed
EP-0907635-A1 HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL SK Corporation (KR) 1999-04-14 EP disclosed
US-5854283-A Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol YUKONG LIMITED (KR) 1998-12-29 US disclosed
WO-1998012177-A1 PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS PFIZER INC. (JP) 1998-03-26 WO disclosed
EP-0816316-A1 PROCESS FOR PRODUCING 1,2-ETHANEDIOL DERIVATIVES NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1998-01-07 EP disclosed
WO-1997026241-A1 HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL SK CORPORATION (KR) 1997-07-24 WO disclosed
WO-1994025427-A1 ETHANOLAMINE DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199612-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK1, KLK4 ADRB3 1664/4885ADRB1 1937/4885ADRB2 2658/4885
US-20250065315-A1 IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES SQLE, NFE2L2, FECH ADRB3 1000/4885ADRB1 547/4885ADRB2 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.