Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560927 | 1.00 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL3917396 | 1.00 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL1154749 | 0.85 | ADRB3 (0.49) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL767795 | 0.85 | ADRB3 (0.49) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL2879198 | 0.85 | ADRB3 (0.49) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL3922600 | 0.84 | LMNA (0.46) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL3146631 | 0.84 | LMNA (0.46) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL7105071 | 0.83 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL8098427 | 0.83 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL7107297 | 0.83 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104450801-A | Application of double-enzyme method to asymmetric preparation of (R)-2-chloro-1-(3-chlorphenyl) ethyl alcohol | UNIV JIANGNAN | 2015-03-25 | — | — | CN | claimed |
| CN-102344947-A | Biological enzyme resolution method for preparing (R)-2-chloro-1-(3-chlorphenyl) ethanol with high optical purity | CHONGQING HUIJIAN BIO TECHNOLOGY CO LTD | 2012-02-08 | — | — | CN | claimed |
| US-8008461-B2 | Carbonyl reductase, gene therefor and use thereof | KANEKA CORPORATION (JP) | 2011-08-30 | — | — | US | claimed |
| CN-101302552-B | Method for preparing (R)-2-chlorin-1-(3-chlorphenyl) ethanol by microorganism catalysis | CHONGQING PORTON TECHNOLOGY CO LTD | 2010-12-29 | — | — | CN | claimed |
| US-20090029430-A1 | Novel Carbonyl Reductase, Gene Therefor and Use Thereof | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | claimed |
| EP-1505155-B1 | CARBONYL REDUCTASE, GENE THEREOF AND USE OF THE SAME | KANEKA CORP (JP) | 2008-12-03 | — | — | EP | claimed |
| CN-101302552-A | Method for preparing (R)-2-chlorin-1-(3-chlorphenyl) ethanol by microorganism catalysis | CHONGQING PORTON TECHNOLOGY CO (CN) | 2008-11-12 | — | — | CN | claimed |
| US-7332312-B2 | Polynucleotide encoding a polypeptide having activity in asymmetrically reducing 2-chloro-1-(3'-chlorophenyl)ethanone, for producing optically active 3-hydroxy ester derivatives | KANEKA CORPORATION (JP) | 2008-02-19 | — | — | US | claimed |
| EP-1811021-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREFOR AND USE THEREOF | Kaneka Corporation (JP) | 2007-07-25 | — | — | EP | claimed |
| US-20070037263-A1 | Novel acetoacetyl-coa reductase and process for producing optically active alcohol | KANEKA CORPORATION (JP) | 2007-02-15 | — | — | US | claimed |
| EP-1688480-A2 | NOVEL ACETOACETYL-CoA REDUCTASE AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | KANEKA CORPORATION (JP) | 2006-08-09 | — | — | EP | claimed |
| US-20060046289-A1 | Novel carbonyl reductase, gene thereof and use of the same | KANEKA CORPORATION (JP) | 2006-03-02 | — | — | US | claimed |
| EP-1505155-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND USE OF THE SAME | KANEKA CORPORATION (JP) | 2005-02-09 | — | — | EP | claimed |
| US-20040219658-A1 | Process for producing optically active (r)-2-chloro-1-(3'-chlorophenly) ethanol | KANEKA CORPORATION (JP) | 2004-11-04 | — | — | US | claimed |
| EP-1400594-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE (R)-2-CHLORO-1-(3'-CHLOROPHENYL)ETHA NOL | KANEKA CORPORATION (JP) | 2004-03-24 | — | — | EP | claimed |
| CN-104450801-B | A kind of two enzymes method asymmetry prepares the application of (R) 2 chlorine 1 (3 chlorphenyl) ethanol | 江南大学 | 2018-04-13 | — | — | CN | disclosed |
| US-9040265-B2 | Oxidoreductases for the stereoselective reduction of keto compounds | IEP GMBH (DE) | 2015-05-26 | — | — | US | disclosed |
| EP-0579770-B1 | MACROCYCLIC LACTAM PROKINETIC AGENTS | ABBOTT LAB (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5495054-A | REDUCING PROCHIRAL KETONES TO ENANTIOMERICALLY PURE ALCOHOLS WITH BORANE REDUCING AGENT | SEPRACOR, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1995032937-A1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR, INC. (US) | 1995-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029430-A1 | Novel Carbonyl Reductase, Gene Therefor and Use Thereof | AKR1C4, CBR3, FAR1 | ADRB3 2460/4885ADRB1 2637/4885ADRB2 3635/4885 |
| US-20060046289-A1 | Novel carbonyl reductase, gene thereof and use of the same | CBR3, CBR1, ADH1C | ADRB3 2609/4885ADRB1 2248/4885ADRB2 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.