Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573038 | 0.89 | PTGS2 (0.47) | PTGS2CYP1A2MAOBCA12CA1 | |
| SCHEMBL8750844 | 0.86 | CA12 (0.53) | CA12CA1CA2TYRCA7 | |
| SCHEMBL11546062 | 0.85 | HDAC2 (0.60) | PTGS2CYP1A2MAOBLMNAMEN1 | |
| SCHEMBL11620573 | 0.85 | CYP1A2 (0.52) | PTGS2CYP1A2MAOBKDM4ELMNA | |
| SCHEMBL11546773 | 0.85 | CYP1A2 (0.57) | PTGS2CYP1A2MAOBKDM4EMEN1 | |
| SCHEMBL11436566 | 0.84 | PTGS2 (0.66) | PTGS2MAOBCA12CA1CA2 | |
| SCHEMBL7769013 | 0.83 | CA12 (0.55) | MAOBCA12CA1CA2TYR | |
| Methyl 3-(4-Chlorophenyl)Acrylate SCHEMBL198277 | 0.83 | CA12 (0.70) | PTGS2CYP1A2MAOBCA12CA1 | |
| Methyl 3-(4-Chlorophenyl)Acrylate SCHEMBL198278 | 0.83 | CA12 (0.70) | PTGS2CYP1A2MAOBCA12CA1 | |
| Methyl 3-(4-Chlorophenyl)Acrylate SCHEMBL6315457 | 0.83 | CA12 (0.70) | PTGS2CYP1A2MAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144351-A | ANTICHOLESTEROL | KLINGE PHARMA GMBH & CO. (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4109013-A | SUBSTITUTED PROPANOL-(2) DERIVATIVES OF HYDROXAMIC ACIDS AND THE USE THEREOF AS HYPOLIPEMIC DRUGS | KLINGE PHARMA GMBH & CO. (DE) | 1978-08-22 | — | — | US | disclosed |
| US-4073935-A | Substituted propanol-(2)-derivatives and their nicotinic acid esters, and process for their preparation, and the use thereof as hypolipemic drugs | KLINGE PHARMA GMBH & CO. (DT) | 1978-02-14 | — | — | US | disclosed |