Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750788 | 0.87 | TDP1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11547633 | 0.86 | PTGS2 (0.56) | CA12CA1CA2TYRCA7 | |
| SCHEMBL8750907 | 0.86 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7769013 | 0.86 | CA12 (0.55) | CA12CA1CA2TYRCA7 | |
| SCHEMBL8750883 | 0.83 | FDPS (0.62) | CA12CA1CA2TYRCA7 | |
| SCHEMBL14634609 | 0.82 | CA12 (0.62) | CA12CA1CA2TYRCA7 | |
| SCHEMBL14634610 | 0.82 | CA12 (0.62) | CA12CA1CA2TYRCA7 | |
| SCHEMBL8750908 | 0.82 | AR (0.45) | GSK3BMAPTKDM4EAPPLMNA | |
| SCHEMBL25197350 | 0.82 | MAOB (0.68) | MAPTLMNAALDH1A1 | |
| SCHEMBL9135929 | 0.81 | FDPS (0.70) | MAPTKDM4EAPPFDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539601-B1 | CINNAMIC ACID/GLYCEROL ADDUCT, ULTRAVIOLET ABSORBER, AND DERMATOLOGIC PREPARATION | SHISEIDO CO LTD (JP) | 1997-04-09 | — | — | EP | disclosed |
| EP-0539601-A1 | CINNAMIC ACID/GLYCEROL ADDUCT, ULTRAVIOLET ABSORBER, AND DERMATOLOGIC PREPARATION | SHISEIDO COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |