Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441314 | 0.96 | BRD4 (0.52) | BRD4IDH1HSD17B10MGLLMAPT | |
| SCHEMBL11549547 | 0.90 | BRD4 (0.44) | BRD4HSD17B10MAPTLMNAHTT | |
| SCHEMBL11554573 | 0.89 | ALDH1A1 (0.48) | BRD4HSD17B10MAPTLMNAHTT | |
| SCHEMBL11551182 | 0.89 | CYP1A2 (0.48) | BRD4MAPTLMNAHTTALDH1A1 | |
| SCHEMBL11441378 | 0.89 | BRD4 (0.43) | BRD4HSD17B10FAAHMGLLMAPT | |
| SCHEMBL11554969 | 0.89 | BRD4 (0.43) | BRD4MAPTLMNAPTGS2 | |
| SCHEMBL11552061 | 0.86 | BACE1 (0.50) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11551147 | 0.86 | MEN1 (0.43) | BRD4MGLLMAPTLMNAPTGS2 | |
| SCHEMBL11553121 | 0.86 | TP53 (0.42) | BRD4FAAHMGLLMAPTLMNA | |
| SCHEMBL11554582 | 0.84 | BACE1 (0.54) | BRD4MAPTALDH1A1PTGS2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |