Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547644 | 0.96 | BRD4 (0.48) | BRD4HSD17B10LMNAMAPTHTT | |
| SCHEMBL11549547 | 0.90 | BRD4 (0.44) | BRD4HSD17B10LMNAMAPTHTT | |
| SCHEMBL11554969 | 0.89 | BRD4 (0.43) | BRD4LMNAMAPTMETELAVL1 | |
| SCHEMBL11441378 | 0.89 | BRD4 (0.43) | BRD4HSD17B10LMNAMAPTHTT | |
| SCHEMBL11551182 | 0.89 | CYP1A2 (0.48) | BRD4LMNAMAPTHTTKDM4E | |
| SCHEMBL11554573 | 0.89 | ALDH1A1 (0.48) | BRD4HSD17B10LMNAMAPTHTT | |
| SCHEMBL11553976 | 0.88 | BRD4 (0.46) | BRD4HSD17B10LMNAMAPTHTT | |
| SCHEMBL11551750 | 0.87 | BRD4 (0.47) | BRD4HSD17B10CREBBPKDM4EALDH1A1 | |
| SCHEMBL11426297 | 0.87 | BRD9 (0.53) | BRD4HSD17B10MAPTCREBBPALDH1A1 | |
| SCHEMBL11549258 | 0.86 | BRD4 (0.44) | BRD4HSD17B10LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |