Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.46 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547663 | 1.00 | RELA (0.56) | RELANFE2L2MAOBCYP19A1MAOA | |
| Diethylamine SCHEMBL10429608 | 0.85 | RELA (0.43) | RELANFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL16687611 | 0.85 | SRD5A1 (0.55) | PTPN1HNF4A | |
| SCHEMBL133329 | 0.84 | APP (0.49) | RELANFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL639671 | 0.84 | RELA (0.54) | RELANFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL639672 | 0.84 | RELA (0.54) | RELANFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL44503 | 0.82 | NFE2L2 (0.68) | RELANFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL44502 | 0.82 | NFE2L2 (0.68) | RELANFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL9540538 | 0.82 | NFE2L2 (0.68) | RELANFE2L2MAOBCYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL7653143 | 0.82 | NFE2L2 (0.68) | RELANFE2L2MAOBCYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |