Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550263 | 0.82 | L3MBTL1 (0.51) | SMN1; SMN2ALDH1A1L3MBTL1HTR2AHTR2C | |
| SCHEMBL11547706 | 0.79 | MAPT (0.46) | SMN1; SMN2ALDH1A1L3MBTL1ABCC1MAPT | |
| Hydrochloric Acid SCHEMBL11547741 | 0.77 | BLM (0.57) | SMN1; SMN2ALDH1A1ABCC1MAPTKDM4E | |
| SCHEMBL11547273 | 0.76 | SMPD1 (0.55) | SMN1; SMN2ABCC1MAPTTP53POLB | |
| Hydrochloric Acid SCHEMBL11546150 | 0.75 | BLM (0.55) | SMN1; SMN2ABCC1MAPTTP53POLB | |
| SCHEMBL11547844 | 0.71 | TP53 (0.51) | SMN1; SMN2ALDH1A1MAPTTP53POLB | |
| SCHEMBL1969501 | 0.70 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1L3MBTL1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11547406 | 0.67 | PMP22 (0.52) | SMN1; SMN2HTR2AHTR2CHTR2BABCC1 | |
| Hydrochloric Acid SCHEMBL11547035 | 0.67 | SMPD1 (0.48) | MAPTCYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL11546728 | 0.67 | PDE5A (0.47) | ALDH1A1HTR2AHTR2CHTR2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134980-A | Phenylalkylamino-alkyl derivatives of quinazolinone and phthalazinone | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-16 | — | — | US | disclosed |