SCHEMBL11547714

SCHEMBL11547714

Cc1cc([N+](=O)[O-])c(O)cc1[N+](=O)[O-]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 5/20 0.52
ALDH1A1 P00352 5/20 0.50
TSHR P16473 4/20 0.48
MAPK1 P28482 3/20 0.48
HPGD P15428 2/20 0.48
TP53 P04637 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
SNCA P37840 1/20 0.48
ALOX15 P16050 3/20 0.47
HSD17B10 Q99714 3/20 0.47
CYP3A4 P08684 2/20 0.47
CYP1A2 P05177 2/20 0.47
RECQL P46063 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALOX12 P18054 2/20 0.46
MAPT P10636 2/20 0.44
ALDH5A1 P51649 1/20 0.44
ABAT P80404 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8580180 0.91 GPR35 (0.52) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL29664349 0.91 GPR35 (0.52) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL29510944 0.89 SNCA (0.55) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL62337 0.89 GPR35 (0.54) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL7937707 0.89 SNCA (0.55) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL10266188 0.87 GPR35 (0.52) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL29535223 0.87 GPR35 (0.52) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL799388 0.87 GPR35 (0.52) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL11835122 0.86 GPR35 (0.60) GPR35ALDH1A1TSHRMAPK1HPGD
SCHEMBL8053279 0.86 TSHR (0.58) GPR35ALDH1A1TSHRHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110776412-B Method for preparing isovaleric acid, ligand, complex and application thereof in catalytic system 万华化学集团股份有限公司 2022-04-22 CN disclosed
CN-110776412-A Method for preparing isovaleric acid, ligand, complex and application thereof in catalytic system 万华化学集团股份有限公司 2020-02-11 CN disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4033945-A Water-soluble trisazo 8-amino-naphthol-1 dyes CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1977-07-05 US disclosed
US-3984405-A PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES E. R. SQUIBB & SONS, INC. (US) 1976-10-05 US disclosed