Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535223 | 1.00 | GPR35 (0.52) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL10266188 | 0.91 | GPR35 (0.52) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL4368022 | 0.89 | GPR35 (0.54) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL7937707 | 0.89 | SNCA (0.55) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL29510944 | 0.89 | SNCA (0.55) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL8580180 | 0.87 | GPR35 (0.52) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL11547714 | 0.87 | GPR35 (0.52) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL29664349 | 0.87 | GPR35 (0.52) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL8053279 | 0.86 | TSHR (0.58) | GPR35ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL62337 | 0.84 | GPR35 (0.54) | GPR35ALDH1A1TSHRCYP1A2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230012449-A1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES, INC. | 2023-01-12 | — | — | US | disclosed |
| CN-110776412-B | Method for preparing isovaleric acid, ligand, complex and application thereof in catalytic system | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| EP-3408332-B1 | BIS-AZO COLORANTS FOR USE AS BLUING AGENTS | MILLIKEN & CO (US) | 2022-03-23 | — | — | EP | disclosed |
| EP-3408368-B1 | BIS-AZO COLORANTS FOR USE AS BLUING AGENTS | PROCTER & GAMBLE (US) | 2021-10-13 | — | — | EP | disclosed |
| US-11078366-B2 | Bis-azo colorants for use as bluing agents | MILLIKEN & COMPANY (US) | 2021-08-03 | — | — | US | disclosed |
| CN-111548649-B | Disazo colorants for use as bluing agents | 美利肯公司 | 2021-07-06 | — | — | CN | disclosed |
| US-11034668-B2 | Compounds for the treatment of HIV | GILEAD SCIENCES, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| CN-111548649-A | Disazo colorants for use as bluing agents | 美利肯公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-108059618-B | Polyfluoropyrimidine-containing aryl amidine compound, and preparation method and application thereof | 浙江省化工研究院有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-108473788-B | Disazo colorants for use as bluing agents | 美利肯公司 | 2020-05-01 | — | — | CN | disclosed |
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |
| US-4975456-A | For inhibiting intestinal absorption of cholesterol and increasing high density lipoprotein | WARNER-LAMBERT COMPANY (US) | 1990-12-04 | — | — | US | disclosed |
| US-4882357-A | ANTICHOLESTEROL AGENT; INCREASES HIGH DENSITY LIPOPROTEINS | WARNER-LAMBERT COMPANY (US) | 1989-11-21 | — | — | US | disclosed |
| US-4880838-A | INSECTICIDES | RHONE-POULENC (NL) | 1989-11-14 | — | — | US | disclosed |
| EP-0215841-B1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION | RHONE-POULENC NEDERLAND B.V. (NL) | 1988-11-17 | — | — | EP | disclosed |
| EP-0215841-A1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION. | UNION CARBIDE CORP (US) | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005780-A1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1986-10-09 | — | — | WO | disclosed |
| US-4487975-A | Etherification of phenols | RHONE-POULENC INDUSTRIES (FR) | 1984-12-11 | — | — | US | disclosed |
| US-4104269-A | Methoxymethoxy protected intermediates for photographic dyes | POLAROID CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4035401-A | Intermediates for photographic dyes | POLAROID CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034668-B2 | Compounds for the treatment of HIV | CCR5, NPC1, FURIN | GPR35 3376/4885ALDH1A1 649/4885TSHR 4824/4885 |
| US-20230012449-A1 | COMPOUNDS FOR THE TREATMENT OF HIV | CCR5, NPC1, FURIN | GPR35 3376/4885ALDH1A1 649/4885TSHR 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.