Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087888 | 1.00 | CYP1A2 (0.56) | CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A | |
| SCHEMBL30270396 | 1.00 | CYP1A2 (0.56) | CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A | |
| SCHEMBL1155486 | 1.00 | CYP1A2 (0.56) | CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A | |
| SCHEMBL12200321 | 1.00 | CYP1A2 (0.56) | CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A | |
| SCHEMBL110315 | 1.00 | CYP1A2 (0.56) | CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A | |
| Acetic Acid SCHEMBL7515736 | 0.90 | ALDH1A1 (0.47) | CYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6055103 | 0.88 | HPRT1 (0.54) | CYP1A2ALDH1A1CYP2C9CYP2C19 | |
| Tetrahydrofuran SCHEMBL971565 | 0.86 | CYP1A2 (0.43) | CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A | |
| SCHEMBL5191146 | 0.86 | SLC6A4 (0.45) | CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A | |
| SCHEMBL19667842 | 0.85 | CYP1A2 (0.46) | CYP1A2ALDH1A1CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574323-B | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-109180496-B | Method for synthesizing cinacalcet by using chemical-enzymatic method | 浙江大学 | 2021-02-09 | — | — | CN | claimed |
| CN-111574323-A | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2020-08-25 | — | — | CN | claimed |
| JP-8225466-A | — | — | None | — | — | JP | disclosed |
| CN-111574323-B | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-111574323-B | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-111574323-B | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-109180496-B | Method for synthesizing cinacalcet by using chemical-enzymatic method | 浙江大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-111574323-A | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111574323-A | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111574323-A | Preparation method of R-1- (naphthalene-1-yl) ethanol | 中山奕安泰医药科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| WO-1999062894-A2 | PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS | THE DOW CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0901997-A1 | Process for producing optically active alcohol compound | Takasago International Corporation (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5763688-A | HYDROGENATING A CARBONYL COMPOUND, RUTHENIUM-PHOSPHINE COMPLEX CATALYST, BASE, DIAMINE | RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) | 1998-06-09 | — | — | US | disclosed |
| JP-H08225466-A | PRODUCTION OF OPTICALLY ACTIVE ALCOHOL | RES DEV CORP OF JAPAN | 1996-09-03 | — | — | JP | disclosed |
| EP-0718265-A2 | Method for producing an alcohol | RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) | 1996-06-26 | — | — | EP | disclosed |
| EP-0398288-B1 | Process for preparing optically active 2-arylalkanoic acids, in particular 2-arylpropionic acids | PUETTER MEDICE CHEM PHARM (DE) | 1995-10-18 | — | — | EP | disclosed |
| US-5096971-A | Acrylic graft copolymer | MITSUBISHI KASEI CORPORATION (JP) | 1992-03-17 | — | — | US | disclosed |
| EP-0398288-A2 | Process for preparing optically active 2-arylalkanoic acids, in particular 2-arylpropionic acids | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1990-11-22 | — | — | EP | disclosed |
| EP-0366042-A2 | Adsorbent for optical resolution and resolution method employing it | MITSUBISHI KASEI CORPORATION (JP) | 1990-05-02 | — | — | EP | disclosed |