Tetrahydrofuran

Tetrahydrofuran

SCHEMBL971565

C1CCOC1.CC(O)c1cccc2ccccc12

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP2C9 P11712 1/20 0.43
SSTR4 P31391 3/20 0.41
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
ADRA2A P08913 2/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
PIK3CB P42338 2/20 0.39
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
PIK3CA P42336 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110315 0.86 CYP1A2 (0.56) CYP1A2CYP2C19ALDH1A1CYP2C9ADRA2A
SCHEMBL30270396 0.86 CYP1A2 (0.56) CYP1A2CYP2C19ALDH1A1CYP2C9ADRA2A
SCHEMBL31087888 0.86 CYP1A2 (0.56) CYP1A2CYP2C19ALDH1A1CYP2C9ADRA2A
SCHEMBL1155486 0.86 CYP1A2 (0.56) CYP1A2CYP2C19ALDH1A1CYP2C9ADRA2A
SCHEMBL1154786 0.86 CYP1A2 (0.56) CYP1A2CYP2C19ALDH1A1CYP2C9ADRA2A
SCHEMBL12200321 0.86 CYP1A2 (0.56) CYP1A2CYP2C19ALDH1A1CYP2C9ADRA2A
Tetrahydrofuran SCHEMBL971244 0.80 TSHR (0.40) CYP1A2CYP2C19ALDH1A1CYP2C9GAA
Furan SCHEMBL28267653 0.79 ALDH1A1 (0.46) CYP1A2CYP2C19ALDH1A1CYP2C9LMNA
Acetic Acid SCHEMBL7515736 0.77 ALDH1A1 (0.47) CYP1A2CYP2C19ALDH1A1CYP2C9METAP2
SCHEMBL6055103 0.75 HPRT1 (0.54) CYP1A2CYP2C19ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829897-B1 SUPPORTED NON-METALLOCENE OLEFIN POLYMERIZATION CATALYST, AND PREPARATION AND USE THEREOF YANGZI PETROCHEMICAL COMPANY CO LTD (CN) 2014-12-10 EP disclosed
US-7875568-B2 reacting silica with titanium tetrachloride to obtain a modified carrier, then mixing with a solution of magnesium chloride, filtering, washing, suction and drying, to prepare a composite carriers, used as supports for addition polymerization catalysts, that improve polymer morphology and bulk density YANGZI PETROCHEMICAL COMPANY CO., LTD. (CN) 2011-01-25 US disclosed
US-20080227936-A1 reacting silica with titanium tetrachloride to obtain a modified carrier, then mixing with a solution of magnesium chloride, filtering, washing, suction and drying, to prepare a composite carriers, used as supports for addition polymerization catalysts, that improve polymer morphology and bulk density YANGZI PETROCHEMICAL COMPANY CO., LTD. (CN) 2008-09-18 US disclosed
EP-1829897-A1 SUPPORTED NON-METALLOCENE OLEFIN POLYMERIZATION CATALYST, AND PREPARATION AND USE THEREOF Yangzi Petrochemical Company Co., Ltd. (CN) 2007-09-05 EP disclosed