Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553515 | 0.96 | TDP1 (0.46) | TDP1PPARGALOX5PTGESLMNA | |
| SCHEMBL11552158 | 0.90 | PPARG (0.42) | TDP1PPARGALOX5PTGESLMNA | |
| SCHEMBL11546174 | 0.88 | PPARG (0.50) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11546853 | 0.87 | PPARG (0.40) | TDP1PPARGALOX5PTGESPPARA | |
| SCHEMBL5210592 | 0.86 | TDP1 (0.54) | TDP1PPARGALOX5PTGESLMNA | |
| SCHEMBL11546727 | 0.83 | TDP1 (0.46) | TDP1PPARGALOX5PTGESLMNA | |
| SCHEMBL11545934 | 0.83 | CTRC (0.51) | PPARGALOX5PTGESPPARACNR2 | |
| SCHEMBL11552397 | 0.83 | CTRC (0.51) | PPARGALOX5PTGESPPARACNR2 | |
| SCHEMBL27504808 | 0.80 | PPARG (0.55) | TDP1PPARGLMNAL3MBTL1PPARA | |
| SCHEMBL767041 | 0.77 | TDP1 (0.55) | TDP1PPARGLMNAL3MBTL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148915-A | ARTERIOSCLEROSIS AND HYPERLIPEMIA TREATMENT DIURETICS, ANTICHOLESTEROL AND ANTILIPEMIC | ALBERT ROLLAND, S.A. (FR) | 1979-04-10 | — | — | US | claimed |
| US-4148915-A | ARTERIOSCLEROSIS AND HYPERLIPEMIA TREATMENT DIURETICS, ANTICHOLESTEROL AND ANTILIPEMIC | ALBERT ROLLAND, S.A. (FR) | 1979-04-10 | — | — | US | disclosed |