Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 17/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545934 | 0.94 | CTRC (0.51) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11552397 | 0.94 | CTRC (0.51) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11552158 | 0.88 | PPARG (0.42) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11548178 | 0.88 | TDP1 (0.47) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11546853 | 0.85 | PPARG (0.40) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11181737 | 0.85 | PPARA (0.61) | PPARGPPARA | |
| SCHEMBL289442 | 0.85 | PPARG (0.64) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL8935884 | 0.85 | PPARG (0.64) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11553515 | 0.84 | TDP1 (0.46) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11547048 | 0.83 | ALDH1A1 (0.42) | PPARGALOX5PTGESPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148915-A | ARTERIOSCLEROSIS AND HYPERLIPEMIA TREATMENT DIURETICS, ANTICHOLESTEROL AND ANTILIPEMIC | ALBERT ROLLAND, S.A. (FR) | 1979-04-10 | — | — | US | claimed |
| US-4148915-A | ARTERIOSCLEROSIS AND HYPERLIPEMIA TREATMENT DIURETICS, ANTICHOLESTEROL AND ANTILIPEMIC | ALBERT ROLLAND, S.A. (FR) | 1979-04-10 | — | — | US | disclosed |