Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407477 | 0.90 | ALDH1A1 (1.00) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL9278806 | 0.85 | ALDH1A1 (0.90) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL11108367 | 0.83 | ALDH1A1 (0.74) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL11103811 | 0.83 | ALDH1A1 (0.74) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL8357191 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL4520992 | 0.81 | ALDH1A1 (0.77) | ALDH1A1TP53GAALMNASMN1; SMN2 | |
| SCHEMBL13889021 | 0.81 | ALDH1A1 (0.81) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL10453840 | 0.80 | ALDH1A1 (0.96) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL3913371 | 0.79 | ALDH1A1 (0.79) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL1287271 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TP53GAATAAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004011-A1 | Phenoxyalkylcarboxylic-acid derivatives, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1979-09-19 | — | — | EP | disclosed |