SCHEMBL11548382

SCHEMBL11548382

O=P(Cl)(Cl)Oc1ccccc1Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
CTNNB1 P35222 1/20 0.43
TSHR P16473 2/20 0.42
LTA4H P09960 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
HTT P42858 2/20 0.42
ALDH1A1 P00352 2/20 0.42
SRC P12931 1/20 0.42
MAPK1 P28482 1/20 0.42
RIPK1 Q13546 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
HTR1A P08908 1/20 0.41
SLC6A3 Q01959 1/20 0.41
DPP4 P27487 1/20 0.41
NR1H2 P55055 1/20 0.39
HRH1 P35367 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906266 0.83 LMNA (0.48) LMNAGAAKMT2ACTNNB1TSHR
SCHEMBL11548387 0.81 LMNA (0.43) LMNAGAAKMT2ACTNNB1TSHR
SCHEMBL22367672 0.80 SRC (0.63) LMNAGAAKMT2ACTNNB1TSHR
SCHEMBL259733 0.78 SRC (0.58) LMNAGAAKMT2AL3MBTL1HTT
SCHEMBL51822 0.78 LTA4H (0.69) LMNAGAAKMT2ACTNNB1TSHR
SCHEMBL4633888 0.75 CA1 (0.56) LMNAKMT2ATSHRL3MBTL1HTT
Bromide SCHEMBL8447011 0.75 LTA4H (0.65) LMNAGAAKMT2ACTNNB1TSHR
SCHEMBL3893178 0.75 LTA4H (0.65) LMNAGAAKMT2ACTNNB1TSHR
SCHEMBL5852017 0.75 LTA4H (0.65) LMNAGAAKMT2ACTNNB1TSHR
Ammonia Solution, Strong SCHEMBL7127955 0.75 LTA4H (0.65) LMNAGAAKMT2ACTNNB1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154716-A SOLID MODIFIER, NONAMINE CATALYST THE DOW CHEMICAL COMPANY (US) 1979-05-15 US disclosed
US-4075151-A SOLID, RAPID-SETTING, RIGID POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1978-02-21 US disclosed
US-4067834-A FATTY ACID OR FATTY OIL, ORGANOTIN CATALYST THE DOW CHEMICAL COMPANY (US) 1978-01-10 US disclosed
US-4060509-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1977-11-29 US disclosed
US-4038235-A SOLID, RAPID-SETTING, RIGID POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1977-07-26 US disclosed
US-4035331-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1977-07-12 US disclosed
US-4028304-A AMINE INITIATED POLYOL, ORGANIC ISOCYANATE, AND A LIQUID MODIFIER THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-4028301-A AMINE INITIATED POLYOL, POLYISOCYANATE, AND A LIQUID MODIFIER THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-4028303-A AMINE INITIATED POLYOL, AROMATIC POLYISOCYANATE, AND A LIQUID MODIFIER THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-4028296-A AMINE-INITIATED POLYETHER POLYOL, CATALYST-FREE, CYCLIC ETHER THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-3983064-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983065-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983066-A Solid, rapid setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983069-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983063-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983068-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3966662-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-06-29 US disclosed
US-3966664-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-06-29 US disclosed
US-3965073-A Preparation of rapid setting non-elastomeric polyurethane compositions in the presence of ester-modified polyoxyalkylene compounds THE DOW CHEMICAL COMPANY (US) 1976-06-22 US disclosed
US-3956221-A Rapid setting non-elastomeric polyurethane compositions containing a non-hydroxyl containing ester-modified polyoxylkylene compound THE DOW CHEMICAL COMPANY (US) 1976-05-11 US disclosed