Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574662 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP3A4ALOX15HSD17B10CCR6 | |
| SCHEMBL7748508 | 0.78 | CYP3A4 (0.63) | ALDH1A1CYP3A4ALOX15HSD17B10HPGD | |
| SCHEMBL11546861 | 0.70 | ALDH1A1 (0.54) | ALDH1A1CYP3A4ALOX15HSD17B10MAPT | |
| SCHEMBL3178940 | 0.70 | AR (0.58) | ALDH1A1CCR6MAPTPKMHSP90AA1 | |
| SCHEMBL710745 | 0.68 | TLR9 (0.59) | ALDH1A1HSD17B10CCR6MAPTPKM | |
| SCHEMBL29510755 | 0.68 | TLR9 (0.59) | ALDH1A1HSD17B10CCR6MAPTPKM | |
| SCHEMBL11539233 | 0.68 | ALDH1A1 (0.46) | ALDH1A1CYP3A4ALOX15HSD17B10MAPT | |
| SCHEMBL14656749 | 0.68 | ALDH1A1 (0.58) | ALDH1A1CCR6MAPTPKMHSP90AA1 | |
| SCHEMBL10586556 | 0.68 | CCR6 (0.60) | ALDH1A1CCR6MAPTPKMHSP90AA1 | |
| SCHEMBL11647855 | 0.67 | ALDH1A1 (0.58) | ALDH1A1CCR6MAPTPKMHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174342-A | N-(Acenaphthenyl)maleimides | ABBOTT LABORATORIES (US) | 1979-11-13 | — | — | US | claimed |
| US-4174342-A | N-(Acenaphthenyl)maleimides | ABBOTT LABORATORIES (US) | 1979-11-13 | — | — | US | disclosed |