Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81530 | 0.88 | MMP2 (0.47) | HRH3MAPTMMP2MMP12POLB | |
| SCHEMBL11549957 | 0.86 | HRH3 (0.47) | HRH3MAPTMMP2LTA4HPTGS2 | |
| SCHEMBL11552305 | 0.84 | FFAR1 (0.42) | HRH3MAPTMMP2MMP12LTA4H | |
| SCHEMBL6298845 | 0.83 | LTA4H (0.52) | HRH3MMP2MMP12LTA4HFFAR1 | |
| SCHEMBL11557111 | 0.82 | MMP2 (0.43) | HRH3MAPTMMP2MMP12POLB | |
| SCHEMBL11555336 | 0.81 | HRH3 (0.44) | HRH3MMP2MMP12LTA4HMELK | |
| SCHEMBL11555947 | 0.81 | HRH3 (0.44) | HRH3MMP2MMP12LTA4HPTGS2 | |
| SCHEMBL26668449 | 0.79 | MMP2 (0.48) | HRH3MMP2MMP12LTA4HFFAR1 | |
| SCHEMBL11552765 | 0.78 | HRH3 (0.40) | HRH3MMP2MMP12LTA4HPOLB | |
| SCHEMBL6446069 | 0.77 | MMP2 (0.55) | HRH3MMP2MMP12POLBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |