Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CCNC | P24863 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548707 | 1.00 | MAPT (0.64) | MAPTTHRBKMT2ATP53CCNC | |
| SCHEMBL12736338 | 0.94 | KMT2A (0.68) | MAPTTHRBKMT2ATP53CCNC | |
| SCHEMBL11943005 | 0.94 | KMT2A (0.68) | MAPTTHRBKMT2ATP53CCNC | |
| SCHEMBL26832413 | 0.92 | TP53 (0.59) | MAPTTHRBKMT2ATP53LMNA | |
| SCHEMBL12154284 | 0.92 | TP53 (0.59) | MAPTTHRBKMT2ATP53LMNA | |
| SCHEMBL11550359 | 0.92 | TP53 (0.59) | MAPTTHRBKMT2ATP53LMNA | |
| SCHEMBL9905987 | 0.88 | KMT2A (0.73) | MAPTTHRBKMT2ACCNCCDK8 | |
| SCHEMBL12736340 | 0.88 | MAPT (0.59) | MAPTTHRBKMT2ATP53CCNC | |
| SCHEMBL2455357 | 0.88 | KMT2A (0.73) | MAPTTHRBKMT2ACCNCCDK8 | |
| SCHEMBL11549784 | 0.88 | LMNA (0.62) | MAPTTHRBKMT2ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136053-A | BIPHENYL ESTERS AND LIQUID CRYSTALLINE MIXTURES COMPRISING THEM | MERCK PATENT GESELLSCHAFT MIT BESCHANKTER HAFTUNG (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4065489-A | Biphenyl esters and liquid crystalline mixtures comprising them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-12-27 | — | — | US | disclosed |