Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747632 | 0.93 | ESR1 (0.63) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| SCHEMBL2747630 | 0.93 | ESR1 (0.63) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| Benzene SCHEMBL27868814 | 0.93 | ESR1 (0.74) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| SCHEMBL55433 | 0.93 | ESR1 (0.74) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| Phosphine SCHEMBL28461311 | 0.90 | ESR1 (0.71) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| SCHEMBL30366689 | 0.90 | ESR1 (0.71) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| SCHEMBL4272880 | 0.90 | ESR1 (0.71) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| SCHEMBL4612465 | 0.90 | ESR1 (0.78) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| Hydrochloric Acid SCHEMBL28642233 | 0.90 | ESR1 (0.71) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| Bromide SCHEMBL28733230 | 0.90 | ESR1 (0.71) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787551-B2 | Cross-linked polymer networks and methods of making and using same | CORNELL UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-20160002421-A1 | CROSS-LINKED POLYMER NETWORKS AND METHODS OF MAKING AND USING SAME | CORNELL UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
| WO-2014172020-A2 | CROSS-LINKED POLYMER NETWORKS AND METHODS OF MAKING AND USING SAME | CORNELL UNIVERSITY (US) | 2014-10-23 | — | — | WO | disclosed |
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |